Figure 4. Long time-dependence of the diffusion coefficient in the tumor.

Both A. in vivo and B. ex vivo PGSE-based D(τ) decrease linearly with 1/τ. Standard deviations within the tumor ROI are represented by the blue / red areas. C. Comparison of the ECS diffusivities derived from the POMACE model (D_ecs, white) with values extrapolated from the PGSE data in the long time regime ( $D_{\mathit{ecs}}^{\infty }$, grey), and from the short-time regime at f_OGSE = 88 Hz (black) for in vivo (left column) and ex vivo (right column) PGSE measurements.