Fig. 5.
SCI increases P-STAT3 Ser in neurons and macrophages/microglia. Double labeling immunocytochemistry was used to identify cells with SCI-induced increases in P-STAT3 Ser. As shown, P-STAT3 Ser (red, B, F, J) was expressed by both neurons (NeuN+; A–D) and macrophages/microglia (ED1+; E–H), but not by GFAP+ astrocytes (I–L) 4 days after complete transection of T8 spinal cord. Scale bar, 20 μm. The boxed area shows higher magnification of co-localized cells (arrow).