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Modulation of deuterium incorporation by hE3 disease-causing variants. The difference plots display the deviations in deuterium incorporation by peptic fragments of hE3 variants (ΔΔD, y axis, deuterium incorporation by the hE3 variant minus deuterium incorporation by hE3). Results represent the mean ± S.D. from three independent experiments. Vertical error bars represent 1 SD in each direction.
