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. 2016 Jul 23;33(7):727–739. doi: 10.1007/s10585-016-9813-y

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 1 — Representative images of high densities of a CD3+, b CD8+, c CD45RO+ and d FoxP3+ TILs (DAB; brown) in pulmonary metastases. e CD3+ tertiary lymphoid structure at the invasive margin between tumor cells and lung parenchyma (magnification ×200/400). (Color figure online)