Fig. 1.

Overlap of genes modulated by C1q. HMDM pooled from 10 healthy donors were incubated with 10 µg protein/ml oxLDL or acLDL in the absence or presence of 75 µg/ml C1q for 3 h at 37 °C in triplicate. Differentially expressed genes from RNA-sequencing were determined using Cyber-T software (n=3, p<0.05, t-test). Libraries were compared to each other to show the intersection of all significant genes upregulated, or downregulated by C1q between acLDL or oxLDL treatment.