Figure 5.
Quantification of DTI and Col1 data obtained from human breast cancer specimens. Significantly lower (A) ADC values and (B) FA values were observed in regions that contained sparse Col1 fibers compared to regions with dense Col1 fiber content (ADC: P = .047, FA: P = .057, N = 3). (C) Representative fiber content mask of dense (red), intermediate-1 (gray), intermediate-2 (green) and sparse fibers (blue). Significantly lower (D) ADC and (E) FA values were observed in the wavy texture pattern as compared to straight texture pattern regions (ADC: P = .006, FA: P = .055, N = 3). (F) Representative texture analysis mask of straight (red), mixed (green) and wavy fibers (blue). Values represent Mean ± SEM. **P ≤ .01, *P < .05.