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. 2016 Sep 15;25(18):1366–1375. doi: 10.1089/scd.2016.0156

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Copyright 2016, Mary Ann Liebert, Inc.

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FIG. 4. — DNA methylation of EDC genes. (A) EDC on chromosome 1. Pale yellow background indicates genes involved in keratinocyte terminal differentiation which with methylation we analyzed individually. (B) DNA methylation of TCHH family shown as lollipop diagram and bar charts. In the lollipop diagram, black circles represent CpG sites that have Beta value ≥0.5 and white circles represent CpG sites with Beta value <0.5. The difference of 0.4 (40%) is considered significant (star) in a bar chart diagram. EDC, epidermal differentiation complex; TCHH, trichohyalin.