Table 4.

The associations of T stage and PSA levels for rs752822 and rs2735839

		T stage		Log-transformed PSA
SNPa	Risk allele	OR (95% CI)	P value	β (95% CI)	P value
Phases I and II: PCa patient cohort (N = 1762)
rs752822	T	0.88 (0.74–1.05)	0.17	0.03 (−0.02 to 0.08)	0.28
rs2735839	A	1.10 (0.88–1.37)	0.41	−0.15 (−0.22 to −0.09)	2.19×10−6
Phase III: AS cohort (N = 494)
rs752822	T	0.96 (0.51–1.79)	0.89	0.015 (−0.10 to 0.13)	0.80
rs2735839	A	0.68 (0.32–1.45)	0.32	−0.31 (−0.44 to −0.17)	1.1×10−5

The models were adjusted for age, ethnicity, Gleason score, T stage and PSA levels at diagnosis where appropriate.

^aDominant genetic model was tested for all SNPs due to small sample size in subcategories.