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. 2016 Sep 23;16:753. doi: 10.1186/s12885-016-2783-2

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Serum DNA predominates in EVs. a EVs were characterized by the exosome specific expression of CD63 and TSG101 by western blotting. b EVs DNA isolated from serum pretreated with DNase I or not was detected by PCR amplification. Serum^EV+ represents EVs-contained serum, Serum^EV- represents EVs-depleted serum