Table 1.
Demographic characteristics and disease/treatment history (N = 150)
| Characteristics | |
|---|---|
| Male | 68 (45%) |
| Right-handed | 131 (87%) |
| Caucasiana | 133 (89%) |
| Age at study entry (y) | |
| Mean (SD) | 51 (13.4) |
| Median (range) | 52 (21–83) |
| Mean education (y) | 16 (2.8) |
| Mean estimated VIQ | 112 (8.6) |
| Tumor type | |
| Low-grade glioma | 34 (23%) |
| High-grade glioma | 57 (38%) |
| Primary CNS lymphoma | 42 (28%) |
| Other | 17 (11%) |
| Tumor location | |
| Frontal/frontal-temporal/frontal-parietal | 81 (54%) |
| Temporal/parietal/occipital | 36 (24%) |
| Cortical/subcortical | 33 (22%) |
| Predominant tumor side | |
| Left | 53 (36%) |
| Right | 68 (45%) |
| Bilateral | 29 (19%) |
| Treatment typeb | |
| RT ± chemotherapy | 150 (70%) |
| Chemotherapy | 45 (30%) |
| Time since treatment completion, mo | |
| Mean (SD) | 45 (50.7) |
| Median (range) | 27 (6–370)c |
| Relapse historyd | 37 (25%) |
| Smoking history | |
| Yes | 66 (44%) |
| Vascular risk | |
| Yes | 58 (39%) |
| Antiepilepticse | |
| Yes | 76 (51%) |
Abbreviations: mo, months; RT, Radiotherapy; SD, Standard Deviation; VIQ, Verbal IQ; y, years.
aAdditional ethnicity: Asian = 5%, Black = 4%, Other = 2%.
bTreatment history = all therapy received including at relapse, if applicable.
cTwo patients had longer time since treatment completion compared with others (ie, highest values = 370 & 314 months; third highest value = 155 months).
dHistory of disease relapse prior to study participation.
eMedication at the time of the cognitive evaluation.