Table 5.

Associations Between Amygdala BOLD Responses and Neuropsychiatric Measures in Each Group

Neuropsychiatric/Psychosocial Domain	HC Group							HIV+ Group
	Model Statistics				Predictor			Model Statistics				Predictor
	R2	F	df	p	β	t	p	R2	F	df	p	β	t	p
Composite Index	.03	.31	2,24	.74	−.06	−0.29	.78	.44	9.70	2,27	<.01	−.44	−2.90	.01
Depression (CESD)	.02	.27	2,24	.77	−.01	−0.03	.98	.35	6.84	2,27	<.01	−.33	−2.03	.05
Anxiety (BAI)	.03	.28	2,24	.76	−.03	−0.14	.89	.38	7.71	2,27	<.01	−.37	−2.33	.03
Apathy (AES)	.04	.43	2,24	.65	−.12	−0.57	.58	.29	4.79	2,26	.02	−.21	−1.13	.27
Alexithymia (TAS)	.06	.70	2,24	.51	.19	0.92	.37	.45	10.05	2,27	<.01	−.45	−2.99	.01
Interpersonal Problems (IIP)	.08	.96	2,24	.39	−.24	−1.17	.25	.34	6.22	2,26	.01	−.31	−1.85	.08

Note: These data summarize results from linear regression analyses conducted in each group. Each model assesses the relation between bilateral amygdala response and a single neuropsychiatric domain (predictor) controlling for MR acquisition site. The Composite Index is a measure of the overall degree of neuropsychiatric difficulty reported across all domains assessed. BOLD = blood oxygen level dependent; HC = HIV-negative Control; CESD = Center for Epidemiological Studies-Depression Scale; BAI = Beck Anxiety Inventory; AES = Apathy Evaluation Scale; TAS = Toronto Alexithymia Scale; IIP = Inventory of Interpersonal Problems.