Skip to main content
. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Methods. 2016 Apr 7;108:130–141. doi: 10.1016/j.ymeth.2016.04.007

Figure 3. Chemical or genetic synthetic lethality of the WRN helicase inhibitor.

Figure 3

Figure 3

(A) Cancer cells are sensitive to the synergistic effects induced by an agent that causes replication stress and a WRN helicase inhibitor. (B) Fanconi anemia mutant cells are hypersensitive to the synergistic effects induced by low doses of the DNA cross-linking agent mitomycin C and WRN helicase inhibitor.