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Changes in the brain that occur in aging. Genetic changes, physical characteristics, cell-to-cell interactions, physiological changes, and cognitive differences are included. It has been suggested that these underlying physiological underpinning contribute to the symptoms of cognitive decline. AHP, afterhyperpolarization; EPSPs, excitatory postsynaptic potentials; LTP, long-term potentiation; PFC, prefrontal cortex.
