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(A) Multimer analysis of VWF from patient's plasma. (B) Multimer analysis of rmVWF. (C) Western Blot of VWFpp from patients’ plasma. (D) Western Blot of recombinant VWFpp under native and reducing conditions. Arrows point to the mutant propeptide band.
N = normal plasma, P = patient, co = co-expression of wt and mVWF, ho = “homozygous” expression of mVWF, rwt = expression of rwtVWF, mw = molecular weight marker, r = recombinant, wt = wild type, m = mutant.
