TABLE 1.
The trajectories of HAMD, CGI and SDS scores (M ± SD)
| Baseline (n=165) | Week 1 (n=158) | Week 2 (n=139) | Week 4 (n=122) | Week 6 (n=103) | |
|---|---|---|---|---|---|
| Total HAMD | 28.38±5.89 | 23.01±7.02*** | 19.03±6.58*** | 14.72±6.02*** | 11.39±6.27*** |
| Cognitive disturbance | 4.79±1.89 | 3.78±1.81*** | 2.91±1.72*** | 2.02±1.57*** | 1.20±1.41*** |
| Retardation | 11.47±3.60 | 10.22±3.82*** | 8.98±3.88*** | 7.39±3.91*** | 6.29±3.95*** |
| Anxiety/somatization | 7.78±2.80 | 6.02±3.12*** | 5.25±3.05*** | 4.00±2.42*** | 2.68±2.42*** |
| Sleep disturbance | 3.68±1.79 | 2.58±1.97*** | 1.73±1.56*** | 1.31±1.44** | 1.16±1.84 |
| Weight | 0.64±0.75 | 0.25±0.49*** | 0.23±0.47* | 0.12±0.38 | 0.06±0.24 |
| CGI | 5.11±1.08 | 4.60±1.21*** | 3.88±1.19*** | 3.00±1.01*** | 2.20±1.17*** |
| SDS | 72.48±11.67 | 64.69±11.48*** | 59.54±13.01*** | 55.14±11.54*** | 50.32±11.73*** |
Note: Compared to its previous evaluation,
P<0.001,
P<0.01,
P<0.05