Figure 3.

Effect of ‘earlier or shorter’ radiotherapy versus ‘later or longer’ radiotherapy on progression-free survival according to chemotherapy compliance. Each trial is represented by a square, the centre of which denotes the HR of death or tumour progression for that trial comparison, with the horizontal lines showing the 95% CIs. The size of the square is directly proportional to the amount of information contributed by the trial. The clear diamonds represent pooled HRs for the trial groups and the black diamond the overall HRs, with the centre denoting the HR and the extremities the 95% CI. The fixed-effect model was used. CI, confidence interval; CT, chemotherapy; HR, hazard ratio; O-E, observed-expected; RT, radiotherapy.