Table 1.
Calf | Thigh | |||||||
Variable | n | % | Mean | SD | P | Mean | SD | P |
Race | ||||||||
Black | 36 | 46.8 | 1.81 | 0.82 | .10 | 3.94 | 1.50 | .600 |
White | 41 | 53.2 | 2.12 | 0.80 | 4.11 | 1.39 | ||
Diagnosis | ||||||||
Schizophrenia/schizoaffective disorder | 27 | 35.1 | 1.82 | 0.79 | .20 | 3.60 | 1.21 | .060* |
Othera | 50 | 64.9 | 2.06 | 0.83 | 4.26 | 1.51 | ||
Antipsychotic | ||||||||
Group 1b | 10 | 13.0 | 1.93 | 1.16 | .75 | 3.45 | 1.51 | .150 |
Group 2c | 40 | 51.9 | 1.92 | 0.77 | 3.92 | 1.33 | ||
Off antipsychotics | 27 | 35.1 | 2.07 | 0.77 | 4.41 | 1.51 | ||
Metabolic syndrome | ||||||||
Yes | 36 | 46.8 | 1.98 | 0.83 | .99 | 4.17 | 1.62 | .430 |
No | 41 | 53.2 | 1.97 | 0.81 | 3.91 | 1.27 | ||
On statin | ||||||||
Yes | 20 | 26.0 | 2.11 | 1.13 | .49 | 4.02 | 1.85 | .980 |
No | 57 | 74.0 | 1.93 | 0.68 | 4.03 | 1.28 | ||
Smoking status | ||||||||
Yes | 37 | 48.1 | 1.78 | 0.71 | .05** | 3.78 | 1.33 | .140 |
No | 40 | 51.9 | 2.15 | 0.88 | 4.26 | 1.51 |
aPosttraumatic stress disorder (PTSD): n = 14, PTSD/anxiety: n = 2, PTSD/depression: n = 12, PTSD/schizophrenia: n = 2, bipolar disorder: n = 3, depression: n = 16, psychosis not otherwise specified: n = 1.
Medications with lower risk for weight gain: typical antipsychotics, ziprasidone, and aripiprazole. Typical antipsychotics were included in this group because of the small sample size.
Medications with higher risk for weight gain: olanzapine, quetiapine, and risperidone.
Subjects with schizophrenia had reduced thigh compliance at a trend level (P = .060) compared to subjects with other diagnoses.
Calf compliance was significantly reduced in smokers compared to nonsmokers.