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Bacterial burden in lungs and extrathoracic organs. (A) Mtb CFUs in total BAL samples and (B) per gram of lung tissue at killing shown for each animal, with multiple sections of lung sampled per animal; active TB (ATB), latent TB (LTB), reactivator (R) and nonreactivator (NR) groups. (C and D) Bacterial burdens per gram of tissue for (C) bronchial lymph node and (D) spleen. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001, one-way ANOVA with Tukey’s multiple testing correction.
