Table 1.

Comparison of 5′ UTR lengths and PARS features for genes exhibiting significant changes in TE in tif3Δ mutant vs. WT cells at FDR <0.05 at 37 °C

5′ UTR feature	All mRNAs, n = 2,607	∆TEtif3Δ(37) <0.7, n = 255	P value	∆TEtif3Δ(37) >1.4, n = 161	P value
Total length	79.0 ± 1.6	119.3 ± 6.61	<0.0001	60.81 ± 6.57	<0.006
Total PARS	7.75 ± 0.49	18.55 ± 2.03	<0.0001	−2.79 ± 1.68	<0.0001
Average PARS	0.058 ± 0.008	0.147 ± 0.019	<0.002	−0.135 ± 0.049	<0.0001
First30 PARS	3.12 ± 0.26	4.16 ± 0.744	0.24	−1.37 ± 1.48	<0.0001
Start30 PARS	4.59 ± 0.31	7.08 ± 0.923	<0.02	−0.037 ± 1.58	<0.0005
Max30 PARS	14.8 ± 0.31	19.31 ± 0.917	<0.0001	8.5 ± 1.50	<0.0001
Plus15 PARS	9.15 ± 0.31	9.61 ± 0.944	0.66	7.44 ± 1.45	0.19
Plus30 PARS	8.84 ± 0.33	10.15 ± 0.936	0.23	8.57 ± 1.53	0.84
Plus45 PARS	9.01 ± 0.33	10.62 ± 1.002	0.14	8.99 ± 1.48	0.99
Plus60 PARS	9.38 ± 0.32	11.29 ± 1.14	0.08	8.86 ± 1.4	0.70
Plus75 PARS	9.65 ± 0.33	12.06 ± 1.03	<0.03	8.00 ± 1.25	0.22

The mean (± SEM) 5′ UTR length or indicated PARS feature was calculated for all 2,607 genes or for 255 of the 443 genes having ∆TE_tif3Δ(37) <0.7 that were compiled in the PARS database and for 161 of the 270 genes with ∆TE_tif3Δ(37) >1.4 at FDR <0.05 that were compiled in the PARS database.