Table S4.
HLA class II associations with 1 log10 decline in viremia at 3- or 6-mo postpartum
| Viral load decline: Third trimester to 3-mo postpartum | Viral load decline: Third trimester to 6-mo postpartum | |||||||
| HLA Allele | <1 log10 IU/mL (n = 21) % | ≥1 log10 IU/mL (n = 13), % | P | P-adjusted | <1 log10 IU/mL (n = 12), % | ≥1 log10 IU/mL (n = 14), % | P | P-adjusted |
| DRB1*01:01 | 24 | 23 | 1 | 1 | 8 | 29 | 0.33 | 1 |
| DRB1*01:02 | 0 | 8 | 0.382 | 1 | 0 | 7 | 1 | 1 |
| DRB1*03:01 | 24 | 15 | 0.682 | 1 | 33 | 14 | 0.365 | 1 |
| DRB1*04:01 | 10 | 8 | 1 | 1 | 8 | 14 | 1 | 1 |
| DRB1*04:03 | 0 | 8 | 0.382 | 1 | 0 | 7 | 1 | 1 |
| DRB1*04:04 | 10 | 8 | 1 | 1 | 0 | 0 | 1 | 1 |
| DRB1*04:07 | 5 | 0 | 1 | 1 | 8 | 0 | 0.462 | 1 |
| DRB1*07:01 | 29 | 23 | 1 | 1 | 42 | 21 | 0.401 | 1 |
| DRB1*09:01 | 0 | 8 | 0.382 | 1 | 0 | 7 | 1 | 1 |
| DRB1*10:01 | 0 | 8 | 0.382 | 1 | 0 | 7 | 1 | 1 |
| DRB1*11:01 | 10 | 23 | 0.348 | 1 | 8 | 21 | 0.598 | 1 |
| DRB1*11:04 | 0 | 15 | 0.139 | 0.997 | 0 | 7 | 1 | 1 |
| DRB1*13:01 | 24 | 8 | 0.37 | 1 | 17 | 14 | 1 | 1 |
| DRB1*13:02 | 10 | 8 | 1 | 1 | 17 | 0 | 0.203 | 1 |
| DRB1*14:01 | 5 | 8 | 1 | 1 | 8 | 7 | 1 | 1 |
| DRB1*14:54 | 5 | 8 | 1 | 1 | 0 | 14 | 0.483 | 1 |
| DRB1*15:01 | 38 | 15 | 0.251 | 0.999 | 42 | 21 | 0.401 | 1 |
| DRB1*16:01 | 10 | 0 | 0.513 | 1 | 8 | 0 | 0.462 | 1 |
| DRB3*01:01 | 29 | 23 | 1 | 1 | 33 | 21 | 0.665 | 1 |
| DRB3*02:02 | 38 | 54 | 0.484 | 1 | 33 | 57 | 0.267 | 1 |
| DRB3*03:01 | 10 | 8 | 1 | 1 | 17 | 0 | 0.203 | 1 |
| DRB4*01:01 | 10 | 8 | 1 | 1 | 17 | 7 | 0.58 | 1 |
| DRB4*01:03 | 38 | 46 | 0.728 | 1 | 33 | 43 | 0.702 | 1 |
| DRB5*01:01 | 38 | 15 | 0.251 | 0.999 | 42 | 21 | 0.401 | 1 |
| DRB5*02:02 | 10 | 0 | 0.513 | 1 | 8 | 0 | 0.462 | 1 |
| DQB1*02:01 | 24 | 15 | 0.682 | 1 | 33 | 14 | 0.365 | 1 |
| DQB1*02:02 | 19 | 23 | 1 | 1 | 25 | 21 | 1 | 1 |
| DQB1*03:01 | 19 | 46 | 0.13 | 0.959 | 25 | 36 | 0.683 | 1 |
| DQB1*03:02 | 14 | 23 | 0.653 | 1 | 0 | 21 | 0.225 | 1 |
| DQB1*03:03 | 10 | 8 | 1 | 1 | 17 | 7 | 0.58 | 1 |
| DQB1*05:01 | 24 | 38 | 0.451 | 1 | 8 | 43 | 0.081 | 0.785 |
| DQB1*05:02 | 10 | 0 | 0.513 | 1 | 8 | 0 | 0.462 | 1 |
| DQB1*05:03 | 10 | 15 | 0.627 | 1 | 8 | 21 | 0.598 | 1 |
| DQB1*06:02 | 38 | 15 | 0.251 | 0.999 | 42 | 21 | 0.401 | 1 |
| DQB1*06:03 | 24 | 0 | 0.132 | 0.968 | 17 | 7 | 0.58 | 1 |
| DQB1*06:04 | 10 | 8 | 1 | 1 | 17 | 0 | 0.203 | 1 |
| DQA1*01:01 | 24 | 31 | 0.704 | 1 | 8 | 36 | 0.17 | 0.987 |
| DQA1*01:02 | 52 | 23 | 0.153 | 0.998 | 58 | 21 | 0.105 | 0.962 |
| DQA1*01:03 | 24 | 0 | 0.132 | 0.968 | 17 | 7 | 0.58 | 1 |
| DQA1*01:04 | 10 | 15 | 0.627 | 1 | 8 | 21 | 0.598 | 1 |
| DQA1*01:05 | 0 | 8 | 0.382 | 1 | 0 | 7 | 1 | 1 |
| DQA1*02:01 | 29 | 23 | 1 | 1 | 42 | 21 | 0.401 | 1 |
| DQA1*03:01 | 14 | 23 | 0.653 | 1 | 0 | 21 | 0.225 | 1 |
| DQA1*03:02 | 0 | 8 | 0.382 | 1 | 0 | 7 | 1 | 1 |
| DQA1*03:03 | 10 | 8 | 1 | 1 | 17 | 7 | 0.58 | 1 |
| DQA1*05:01 | 24 | 15 | 0.682 | 1 | 33 | 14 | 0.365 | 1 |
| DQA1*05:05 | 10 | 38 | 0.079 | 0.905 | 8 | 29 | 0.33 | 1 |
| DPB1*01:01 | 19 | 23 | 1 | 1 | 17 | 21 | 1 | 1 |
| DPB1*02:01 | 29 | 23 | 1 | 1 | 25 | 21 | 1 | 1 |
| DPB1*03:01 | 0 | 23 | 0.048 | 0.761 | 0 | 21 | 0.225 | 1 |
| DPB1*04:01 | 81 | 23 | 0.001 | 0.013 | 83 | 36 | 0.021 | 0.266 |
| DPB1*04:02 | 19 | 46 | 0.13 | 0.959 | 8 | 43 | 0.081 | 0.785 |
| DPB1*05:01 | 0 | 15 | 0.139 | 0.997 | 0 | 14 | 0.483 | 1 |
| DPB1*06:01 | 5 | 23 | 0.274 | 1 | 8 | 7 | 1 | 1 |
| DPB1*10:01 | 5 | 0 | 1 | 1 | 8 | 0 | 0.462 | 1 |
| DPB1*11:01 | 0 | 15 | 0.139 | 0.997 | 0 | 14 | 0.483 | 1 |
| DPB1*14:01 | 10 | 8 | 1 | 1 | 8 | 14 | 1 | 1 |
| DPA1*01:03 | 100 | 92 | 0.382 | 1 | 100 | 93 | 1 | 1 |
| DPA1*01:05 | 5 | 0 | 1 | 1 | 8 | 0 | 0.462 | 1 |
| DPA1*02:01 | 29 | 54 | 0.168 | 0.998 | 33 | 57 | 0.267 | 1 |
| DPA1*02:02 | 5 | 8 | 1 | 1 | 0 | 7 | 1 | 1 |
| DPA1*03:01 | 0 | 8 | 0.382 | 1 | 0 | 7 | 1 | 1 |
Boldface entries indicate P < 0.05.