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. 2016 Sep 15;33(18):1696–1708. doi: 10.1089/neu.2015.4111

FIG. 3.

FIG. 3.

Tamoxifen (TAM) promotes neuronal survival in the dorsal and ventral horn at the rostral penumbra after spinal cord injury (SCI). (A) Representative images of NeunN immunoreactivity from the DH or VH in the rostral penumbra at 35 days post-injury (magnification = 20x, scale bar = 100 μm). High power magnification (63x) of dorsal and ventral horn neurons from sham animals (scale bar = 50 μm). (B) Neuronal cell count shows that SCI reduces the total number of neurons in the rostral area. TAM treatment at 0 and 24 h after SCI significantly increases the number of neurons from the DH and VH of injured animals. One-way analysis of variance Tukey's multiple comparison test (**p < 0.01), data are mean ± SEM, sham (PLB+TAM) n = 9, SCI PLB (rats from t = 0 h + 24 h) n = 4, SCI TAM 0 h n = 3, SCI TAM 24 h n = 3.