Table 1. Gerbil neutralizing antibody responses elicited by a CA16 vaccine.
Immunization interval | Vaccine dose (U) | Neutralizing antibodies (1/GMT) |
|||||
---|---|---|---|---|---|---|---|
1w | 2w | 3w | 5w | 8w | 12w | ||
2 weeks | 640 | 45.99 | 25.01 | 20.64 | 30.37 | 8.7 | 6.07 |
160 | 20.06 | 11.00 | 11.23 | 9.77 | 3.23 | 5.15 | |
40 | 19.65 | 4.75 | 1.41 | 0 | 0 | 0 | |
10 | 19.41 | 1.28 | 1.29 | 0 | 0 | 0 | |
2.5 | 2.49 | 0 | 0 | 0 | 0 | 0 | |
4 weeks | 640 | 120.58 | 97.60 | 84.33 | 52.46 | 30.69 | 24.69 |
160 | 179.55 | 113.00 | 26.63 | 30.21 | 30.88 | 13.51 | |
40 | 5.26 | 1.04 | 0 | 0 | 0 | 0 | |
10 | 1.86 | 0 | 0 | 0 | 0 | 0 | |
2.5 | 0 | 0 | 0 | 0 | 0 | 0 |
GMT: geometric mean titers.