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. 2016 Sep 20;8(9):250. doi: 10.3390/v8090250

Figure 10.

Figure 10

Structure of the head region from the H protein of MeV bound to the V region of Nectin-4. (A) Schematic of Nectin-4 showing the V and two C2 regions of the extracellular domain, the membrane spanning region, and the intracellular cytoplasmic tail; (B) Structure derived by X-ray crystallography showing heads of the H protein dimer interacting with the V regions of Nectin-4; (C) Structure of the head from β4 and β5 regions of monomeric H protein interacting with of the V domain of Nectin-4 (Nectin-4v). Adapted by permission from the Nature Publishing Group, Macmillan Publishers Ltd.: Zhang, X.; Lu, G.; Qi, J.; Li, Y.; He, Y.; Xu, X.; Shi, J.; Zhang, C.W.; Yan, J.; Gao, G.F. Nat. Struct. Mol. Biol. 2013, 20, 67–72 [151].