Table 1.
Application of CTVI for different types of viruses.
| Viral Type | Virus | Genome | Viral Protein | Foreign Molecule | Fusion Protein | Location of Enzyme | Plasmid Vector | Cell | Antibiotic | References |
|---|---|---|---|---|---|---|---|---|---|---|
| Retroviruses | Mo-MLV | RNA | Gag/Gag-Pol | SN/RNase HI | Gag-SN/Gag-RNase HI | C-terminus | pGN1600 | RCASBP | [18] | |
| CSFV | RNA | Capsid | SN | Capsid-SN | C-terminus | pcDNA | PK-15 | G418 | [19] | |
| HIV-1 | RNA | Vpr | scAb | Vpr-scAb | C-terminus | pCXN2 | 293T | G418 | [20,21] | |
| Vpr | SN | Vpr-SN | C-terminus | pLR2P | HeLa | [22] | ||||
| Flavivirus | JEV | RNA | Capsid | SN | Capsid-SN | C-terminus | pcDNA3.1 | BHK-21 | [12,23] | |
| DENV2 | RNA | Capsid | SN | Capsid-SN | C-terminus | pcDNA6/V5-His | BHK-21 | blasticidin | [16,17,24] | |
| Circovirus | PCV2 | DNA | Capsid | SN | Capsid-SN | C/N-terminus | pIRESneo | PK15 | G418 | |
| Hepadnaviruses | HBV | DNA | Capsid | Ribonuclease | p/TN | C-terminus | pcDNA3.1 (−) | HepG2.2.15 | [13] | |
| Capsid | SN | Capsid-SN | C-terminus | pcDNA6/Myc-His | Huh7 | [14,25] |
SN: staphylococcal nuclease; Gag: group-specific antigen; Pol: polymerase; Vpr: viral protein R; scAb: single-chain antibody; Moloney murine leukaemia virus (Mo-MLV); classical swine fever virus (CSFV), human immunodeficiency virus-1 (HIV-1); Japanese encephalitis virus (JEV); hepatitis B virus (HBV); dengue 2 virus (DENV2).