Table 1. LV Hemodynamics at 6 weeks after TAC or Sham Surgery.

	Sham	Sham + PBA	TAC	TAC + PBA
LVESP, mmHg	105 ± 3.5	105 ± 3.9	203 ± 11.2†	203 ± 9.3†
LVEDP, mmHg	3.2 ± 0.91	3.4 ± 0.71	15.5 ± 2.00†	31.0 ± 1.85†,#
Contractivity index, 1/s	203 ± 11.6	225 ± 32.6	160 ± 9.9*	120 ± 7.5*,§
τ, ms	8.1 ± 0.80	7.9 ± 0.90	11.3 ± 0.79*	16.5 ± 1.16*,§
Max dP/dt, mmHg/s	10861 ± 433.2	11853 ± 2051.5	8900 ± 814.7	7472 ± 602.9
Min dP/dt, mmHg/s	−10367 ± 783.4	−10433 ± 1275.7	−8519 ± 619.3	−6913 ± 537.3
HR, bpm	509 ± 25	542 ± 29	422 ± 22	427 ± 17

TAC, transverse aortic constriction; HR, heart rate; LVESP, maximum left ventricular end-systolic pressure; LVEDP, left ventricular end-diastolic pressure; Contractility index: Max dP/dt divided by the pressure at the time of Max dP/dt; Tau, the exponential time constant of relaxation; Max dP/dt, the steepest slope during the upstroke of the pressure curve; Min dP/dt, the steepest slope during the downstroke of the pressure curve; Sham (n = 6), Sham + PBA (100 mg/kg/d, n = 6), TAC (n = 10) and TAC + PBA (100 mg/kg/d, n = 8). Data are mean ± S.E.M. ^*P < 0.05, ^†P < 0.001 vs. Sham. ^§P < 0.05, ^#P < 0.001 vs. TAC.