Table 2.
Ref. | Gender age | Renal function | Clinical associations |
[8] | Female 36 yr | ESRD Dialysis | Relapsed Hodgkin’s lymphoma |
[8] | Female 43 yr | ESRD Dialysis | Acute myelogenous leukemia |
[11] | Male 47 yr | ESRD Dialysis | Non-Hodgkin’s lymphoma |
[49] | Male 17 yr | ESRD Dialysis | Myelodysplastic syndrome Severe hemorrhagic cystitis No renal biopsy Death from multi-organ failure |
[50] | Female 28 yr | ESRD Dialysis | Acute myelogenous leukemia Recurrent CMV reactivation |
[51] | NR NR | ARF | Underlying disease NR Adenovirus pneumonia Adenovirus nephritis Death |
[58] | Male 14 yr | Rising SCr | Acute myelogenous leukemia Death from multi-organ failure |
[60] | Male 10 yr | GFR normalized | Acute myelogenous leukemia No renal biopsy |
[63] | Male 51 yr | ESRD Dialysis | Myelodysplastic syndrome Hepatorenal syndrome GVHD Death from Pseudomonas sepsis |
[64] | Male 10 yr | Peak SCr 3.5 mg/dL Scr at 1.7 mg/dL post-treatment | Chronic myelogenous leukemia Adenovirus and bacterial infections Severe GVHD |
[64] | Male 13 yr | ESRD Declined dialysis | Fanconi’s anemia Gram-positive bacteremias Pulmonary aspergillosis Hyperacute GVHD Death |
[70] | Female 10 yr | ESRD Dialysis | Recurrent metastatic neuroendocrine tumor Thrombocytopenia, leukopenia, lymphopenia Antineutrophil-antiplatelet antibodies Death from sepsis |
[75] | Female 10 yr | Peak SCr 1.58 mg/dL SCr at 1.1-1.4 mg/dL post-treatment | Myelodysplastic syndrome Acute GVHD |
[77] | Male 59 yr | CKD stage 5 not requiring dialysis | Myelodysplastic syndrome |
[79] | Male 58 yr | Death due to sepsis eGFR stable at 20 at the time of death | Large B cell lymphoma Acute GVHD |
BK nephropathy was manifested at various times post-heart transplantation. Ages reported in this Table are the calculated ages at the time of diagnosis of BK nephropathy. ESRD: End-stage renal disease; ARF: Acute renal failure; SCr: Serum creatinine; GFR: Glomerular filtration rate; GVHD: Graft vs host disease; NR: Not report.