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. 2016 Sep 24;6(3):472–504. doi: 10.5500/wjt.v6.i3.472

Table 2.

BK nephropathy in recipients of bone marrow or stem cell transplants

Ref. Gender age Renal function Clinical associations
[8] Female 36 yr ESRD Dialysis Relapsed Hodgkin’s lymphoma
[8] Female 43 yr ESRD Dialysis Acute myelogenous leukemia
[11] Male 47 yr ESRD Dialysis Non-Hodgkin’s lymphoma
[49] Male 17 yr ESRD Dialysis Myelodysplastic syndrome Severe hemorrhagic cystitis No renal biopsy Death from multi-organ failure
[50] Female 28 yr ESRD Dialysis Acute myelogenous leukemia Recurrent CMV reactivation
[51] NR NR ARF Underlying disease NR Adenovirus pneumonia Adenovirus nephritis Death
[58] Male 14 yr Rising SCr Acute myelogenous leukemia Death from multi-organ failure
[60] Male 10 yr GFR normalized Acute myelogenous leukemia No renal biopsy
[63] Male 51 yr ESRD Dialysis Myelodysplastic syndrome Hepatorenal syndrome GVHD Death from Pseudomonas sepsis
[64] Male 10 yr Peak SCr 3.5 mg/dL Scr at 1.7 mg/dL post-treatment Chronic myelogenous leukemia Adenovirus and bacterial infections Severe GVHD
[64] Male 13 yr ESRD Declined dialysis Fanconi’s anemia Gram-positive bacteremias Pulmonary aspergillosis Hyperacute GVHD Death
[70] Female 10 yr ESRD Dialysis Recurrent metastatic neuroendocrine tumor Thrombocytopenia, leukopenia, lymphopenia Antineutrophil-antiplatelet antibodies Death from sepsis
[75] Female 10 yr Peak SCr 1.58 mg/dL SCr at 1.1-1.4 mg/dL post-treatment Myelodysplastic syndrome Acute GVHD
[77] Male 59 yr CKD stage 5 not requiring dialysis Myelodysplastic syndrome
[79] Male 58 yr Death due to sepsis eGFR stable at 20 at the time of death Large B cell lymphoma Acute GVHD

BK nephropathy was manifested at various times post-heart transplantation. Ages reported in this Table are the calculated ages at the time of diagnosis of BK nephropathy. ESRD: End-stage renal disease; ARF: Acute renal failure; SCr: Serum creatinine; GFR: Glomerular filtration rate; GVHD: Graft vs host disease; NR: Not report.