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. 2016 Sep 24;6(3):505–516. doi: 10.5500/wjt.v6.i3.505

Table 1.

Epstein-Barr virus-driven lymphoproliferative disorders are linked with particular Epstein-Barr virus latency programs

Latency Expressed EBV gene products Normal B-cell stage Associated disease
III (growth) EBER1-2, EBNA1-6, LMP1, LMP2A-B Activated B lymphoblast PT-DLBCL AIDS-related lymphoma Acute infectious mononucleosis
II (default) EBER 1-2, EBNA1, LMP1- 2A B-cell undergoing the GC reaction PT-DLBCL Classical Hodgkin lymphoma
I EBER 1-2 , EBNA1 Memory B-cell (PT-) Burkitt lymphoma (PT-) PBL

EBER: Epstein-Barr virus-encoded RNA; EBNA: Epstein-Barr virus nuclear antigen; LMP: Latent membrane protein; PT-DLBCL: Post-transplant diffuse large B-cell lymphoma; PBL: Plasmablastic lymphoma; EBV: Epstein-Barr virus.