Skip to main content
. 2016 Sep 22;7:12794. doi: 10.1038/ncomms12794

Figure 7. Inhibition of GDF11 prevents bone loss.

Figure 7

(a) MicroCT reconstruction of trabecular bone from distal femurs. Scale bar, 500 μm. (b) Von Kossa staining of undecalicified sections of femurs. Scale bar, 500 μm. (c) TRAP staining of femur sections. Scale bar, 50 μm. (d) Histomorphometric analysis of the metaphysis region of distal femurs. Results are shown as mean±s.d.; n=6; *P<0.05 and **P<0.01 by t test. (e,f) The serum levels of CTX and P1NP. Results are shown as mean±s.d.; n=6; *P<0.05 by t test. (g) Representative images of microCT scanning of lumber 4 vertebrae. The red circles indicate the region of interest (ROI). Scale bar, 1 mm. (h) Von Kossa staining of undecalicified sections of lumber 4 vertebrae. Scale bar, 500 μm. (i) TRAP staining of vertebrae sections. Scale bar, 50 μm. (j) Histomorphometric analysis of the trabecular bone in lumber four vertebrae. Results are shown as mean±s.d.; n=6; *P<0.05 and **P<0.01 by t test.