Table 2. Hazard ratios (HR) of chemerin levels in predicting the outcomes using Cox proportional hazards regression models with multivariate adjustments.
| Variables | CV event | Composite CV outcome | CV event (death as competing risk) | Composite CV outcome (death as competing risk) |
|---|---|---|---|---|
| Adjusted HR (95% CI) | Adjusted HR (95% CI) | Adjusted HR (95% CI) | Adjusted HR (95% CI) | |
| Chemerin (higher v.s lower) | 0.64 (0.41‒0.98)§ | 0.67 (0.45‒0.89)§ | 0.7 (0.46‒0.89)§ | 0.7 (0.46‒0.89)§ |
| GNRI (every 1 unit increase) | 0.93 (0.89‒0.98)§ | 0.92 (0.82‒0.98)§ | 0.9 (0.79‒0.97)§ | 0.88 (0.75‒0.97)§ |
| Chemerin (adjust for chemerin x GNRI) | ||||
| (higher v.s lower) | 0.38 (0.19‒0.75)ǂ | 0.54 (0.2‒0.8)ǂ | 0.52 (0.24‒0.78)ǂ | 0.58 (0.19‒0.83)ǂ |
| Interaction | 0.04 | 0.007 | 0.02 | 0.004 |
Abbreviations: CV, cardiovascular; HR, hazard ratio; CI, confidence interval; GNRI, geriatric nutritional risk index.
§Adjusted for gender, age; dialysis vintage; presence of diabetes mellitus, patient cohort, waist circumference, geriatric nutritional risk index (GNRI), calcium phosphate product (CaxP), hemoglobin, intact parathyroid hormone (iPTH) and high-sensitive C-reactive protein (hs-CRP) levels.
ǂAdjusted for gender, age; dialysis vintage; presence of diabetes mellitus, patient cohort, waist circumference, geriatric nutritional risk index (GNRI), chemerin x GNRI, calcium phosphate product (CaxP), hemoglobin, intact parathyroid hormone (iPTH) and high-sensitive C-reactive protein (hs-CRP) levels.