Table 1. Mean ranks of eleven dolphin serum proteins not present in the undepleted pooled human serum proteome results.
| Protein Name | ENSEMBl Accession Number | MW | Identified in all 6 dolphins at any time | Dolphin serum | Human serum | Pig serum | Human (Farrah et al.25)plasma |
|
|---|---|---|---|---|---|---|---|---|
| Mean Rank (±SD) | Rank | Rank | Rank | Est. conc.(ng/ml) | ||||
| Fetuin B | ENSTTRP00000015959 | 41 kDa | Yes | 13 ± 1 | — | 57 | 185 | 270 |
| Glutathione peroxidase 3 | ENSTTRP00000005431 | 26 kDa | Yes | 27 ± 4 | — | — | 69 | 10000 |
| Adiponectin | ENSTTRP00000015964 | 26 kDa | Yes | 30 ± 9 | — | — | 265 | 120 |
| Vanin 1 | ENSTTRP00000000565 | 57 kDa | Yes | 36 ± 4 | — | — | 348 | 56 |
| Fibrinogen beta chain | ENSTTRP00000009538 | 56 kDa | No | 44 ± 19 | — | — | 18 | 130000 |
| Fibrinogen gamma chain | ENSTTRP00000011681 | 90 kDa | No | 47 ± 17 | — | — | 21 | 98000 |
| Extracellular matrix protein 1 | ENSTTRP00000010082 | 62 kDa | Yes | 47 ± 3 | — | 73 | 131 | 770 |
| Deleted in malignant brain tumors 1 | ENSTTRP00000004960 | 173 kDa | Yes | 47 ± 4 | — | — | 1176 | N/A |
| Polymeric immunoglobulin receptor | ENSTTRP00000011489 | 83 kDa | Yes | 50 ± 4 | — | — | 465 | 25 |
| Adipocyte plasma membrane protein | ENSTTRP00000001536 | 46 kDa | No | 51 ± 6 | — | — | 379 | 29 |
| Glycosylphosphatidylinositol phospholipase D1 | ENSTTRP00000000260 | 90 kDa | No | 56 ± 3 | — | 76 | 155 | 460 |
Protein ranks for orthologous proteins from the undepleted pig serum proteome and the well characterized human plasma proteome, along with estimated concentrations (Est. Conc.) are provided. MW = predicted molecular weight in kilodaltons. A horizontal dash indicates that no protein was identified. A ‘No’ in the fourth column indicates that proteins were not consistently identified for every dolphin at each time point in the 24 week study21.