Figure 4. Myeloid cell-specific lipin-1 deficiency reduced circulating levels of lipocalin-2 (Lcn2) and serum amyloid A1 (Saa1) in mice after ethanol feeding.

Wild-type (WT) or mLipin-1KO (KO) mice were pair-fed either a control diet or an ethanol-containing diet for 10 days followed by single gavage of ethanol. (A) Relative liver mRNA levels of Lcn2 and Saa1. (B) Representative Western analysis of liver Lcn2 and Saa1. (C) Relative liver protein levels of Lcn2 and Saa1. (D) Relative serum Lcn2 levels. (E) Relative serum Saa1 levels. Results are expressed as means ± SEM (n = 4–6 mice). Means without a common letter differ, P < 0.05.