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. 2016 Sep 26;6:33878. doi: 10.1038/srep33878

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Copyright © 2016, The Author(s)

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(a) Alignment of antibody Fv amino acid sequence of YP7, YP8, YP9 and YP9.1. The numbers reflect the KABAT system. (b) The immunotoxin contains the scFv fused to the N-terminus of a truncated Pseudomonas exotoxin (PE38). (c) SDS-PAGE of purified immunotoxins (IT) of YP7, YP8, YP9 and YP9.1. (d) Binding of immunotoxins on G1 cells. (e) Cytotoxicity of immunotoxins on G1 cells. IT, immunotoxin. The numbers in parentheses are EC₅₀ values of immunotoxins in ng/ml.