Table 1. A summary of 41P in mouse antibody humanization literature between 2009 and November 2015.
| Mouse Ab | Target | Closest mouse VH germline | Original 41P | Retained 41P | Convert to 41P | References |
|---|---|---|---|---|---|---|
| 8H9 | B7-H3 | IGHV1-85*01 | 1 | 1 | 40 | |
| 5F9 | CD47 | IGHV1-12*01 | 1 | 1 | 41 | |
| KR127 | preS1 (HBV) | IGHV1-82*01 | 1 | 1 | 42 | |
| Rituximab | CD20 | IGHV1-12*01 | 1 | 1 | 43 | |
| MR1 | EGFRvIII | IGHV5-6*03 | 0 | 1 | 44 | |
| 30D8 | CXCL12 | IGHV2-6-4*01 | 1 | 1 | 45 | |
| AD11 | hβNGF | IGHV2-6-7*02 | 0 | 1 | 46 | |
| D9 | Ricin | IGHV1-26*01 | 0 | 1 | 47 | |
| ICR62 | EGFR | IGHV1-22*01 | 0 | 1 | 48 | |
| 1567 | CCR4 | IGHV1S56*01 | 1 | 1 | 49 | |
| 3F8 | GD2 | IGHV2-9*02 | 1 | 1 | 50 | |
| αD11 | hβNGF | IGHV2-6-7*02 | 0 | 1 | a different humanization version of AD11 51 | |
| 14F7 | ganglioside | IGHV1-7*01 | 1 | 1 | 52 | |
| 3G8 | CD16 | IGHV8-8*01 | 0 | 1 | 31 | |
| m357 | TNF-α | IGHV6-3*01 | 1 | 1 | 53 | |
| LD1 | FGF receptor 4 | IGHV1-61*01 | 1 | 1 | 54 | |
| muAb2/3H6 | human monoclonal antibody 2F5 antigen binding site | IGKV17-121*01 | 1 | 1 | 55 | |
| m836 | IL-13 | IGHV8-8*01 | 0 | 1 | 56 | |
| tumex | Membrane-Associated Heat Shock Protein 70 | IGHV2-6-4*01 | 1 | 1 | 57 | |
| AY4 | death receptor 4 | IGHV5-6-5*01 | 1 | 1 | 58 | |
| m9O12 | platelet glycoprotein VI | IGHV1-12*01 | 1 | 1 | 59 | |
| 5S | Hepatitis B surface antigen | IGHV1-12*01 | 1 | 1 | 60 | |
| 4G7 | CD19 | IGHV1-14*01 | 1 | 1 | 61 | |
| 3D8 | DNA | IGHV1-14*01 | 1 | 1 | 62 | |
| muA9 | CD16 | IGHV1-63*02 | 1 | 1 | 63 |