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. 2015 Jul 23;65(10):1619–1631. doi: 10.1136/gutjnl-2015-309276

Figure 6.

Figure 6

Suppression of gastric cancer growth by MDGA2 is partly dependent on DNA methyltransferase 1 associated protein 1 (DMAP1). (A) Expression of MDGA2 was not affected by DMAP1. (B) Cell viability of AGS and BGC823 cells by the 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium (MTS) assay. (C) Colony formation in AGS and BGC823 cells. (D) DMAP1 was knocked down in cells with stable MDGA2 over-expression by short interference RNA (siRNA) transfection. (E) Effect on gastric cancer cell growth by different levels of MDGA2 and DMAP1. Cell growth was monitored by the xCelligence system. Data shown are mean±SD. (F) Effect of different levels of MDGA2 and DMAP1 on colony formation ability of gastric cancer cells. *p<0.05, **p<0.001, ***p<0.0001.