Table 1.

Univariate and multivariate Cox regression analyses of potential poor prognostic factors in gastric cancer

	Univariate		Multivariate
Variable	RR (95% CI)	p Value	RR (95% CI)	p Value
Age	1.003 (0.988 to 1.017)	0.719	1.001 (0.987 to 1.014)	0.935
Gender		0.776		0.481
Male	1.056 (0.727 to 1.533)		1.145 (0.785 to 1.670)
Female	1		1
Helicobacter pylori		0.211
Positive	0.850 (0.658 to 1.097)
Negative	1
Lauren		0.284
Intestinal	1.205 (0.856 to 1.697)
Non-intestinal	1
Differentiation		0.387
Low	1.175 (0.815 to 1.693)
Moderate or high	1
TNM stage
I	0.100 (0.043 to 0.235)	<0.0001	0.105 (0.045 to 0.248)	<0.0001
II	0.211 (0.115 to 0.385)	<0.0001	0.215 (0.117 to 0.394)	<0.0001
III	0.249 (0.163 to 0.380)	<0.0001	0.241 (0.157 to 0.369)	<0.0001
IV	1		1
MDGA2 methylation		0.001		0.005
Yes	2.004 (1.314 to 3.057)		1.851 (1.208 to 2.836)
No	1		1

RR, relative risk; TNM, Tumor-Nodes-Metastasis.