Table 1.
Patients Characteristics
| PTC clinicopathologic subtypes | ||||
|---|---|---|---|---|
| Characteristic | PTC (n = 1216) | cPTC (n = 891) | fvPTC (n = 243) | microPTC (n = 328) |
| Average age at diagnosis, M ± SD | 41.3 ± 14.5 | 41.3 ± 14.7 | 39.9 ± 13.3 | 44.0 ± 13.0 |
| Sex | ||||
| Female | 935 (76.9%) | 680(76.3%) | 194 (79.8%) | 274 (83.5%) |
| Male | 281 (23.1%) | 211 (23.7%) | 49 (20.2%) | 54 (16.5%) |
| Ethnicity | ||||
| Afro-American | 42 (3.5%) | 26 (2.9%) | 13 (5.4%) | 8 (2.4%) |
| Asian | 30 (2.5%) | 26 (2.9%) | 3 (1.2%) | 5 (1.5%) |
| Caucasian | 1144 (94.1%) | 839 (94.2%) | 227 (93.4%) | 315 (96.0%) |
| T stage | ||||
| T0 | 2 (0.2%) | 0 (0.0%) | 1 (0.4%) | 2 (0.6%) |
| T1 | 638 (54.3%) | 501 (58.3%) | 112 (47.5%) | 314 (95.7%) |
| T2 | 263 (22.4%) | 171 (19.9%) | 69 (29.2%) | 1 (0.3%) |
| T3 | 218 (18.6%) | 150 (17.5%) | 46 (19.5%) | 10 (3.1%) |
| T4 | 53 (4.5%) | 37 (4.3%) | 8 (3.4%) | 1(0.3%) |
| N stage | ||||
| N0 | 722 (61.6%) | 500 (58.3%) | 186 (78.8%) | 243 (75.0%) |
| N1 | 450 (38.4%) | 357 (41.7%) | 50 (21.2%) | 81 (25.0%) |
| M stage | ||||
| M0 | 1132 (95.9%) | 835 (96.5%) | 222 (94.1%) | 321 (98.5%) |
| M1 | 49 (4.2%) | 30 (3.5%) | 14 (5.93%) | 5 (1.53%) |
| Multifocality | ||||
| No | 582 (49.70%) | 415 (48.59%) | 130 (55.08%) | 181 (55.86%) |
| Yes | 589 (50.30%) | 439 (51.41%) | 106 (44.9%) | 143 (44.1%) |
| Lymphovascular invasion | ||||
| No | 954 (83.0%) | 707 (84.1%) | 189 (82.2%) | 301 (94.1%) |
| Yes | 195 (17.0%) | 134 (15.9%) | 41 (17.8%) | 19 (5.9%) |
| Capsular invasion | ||||
| No | 988 (85.6%) | 740 (87.2%) | 191 (84.1%) | 301 (94.1%) |
| Yes | 166 (14.4%) | 109 (12.8%) | 36 (15.9%) | 19 (5.9%) |
| Extrathyroidal expansion | ||||
| No | 441 (70.7%) | 338 (70.3%) | 75 (75.8%) | 183 (92.4%) |
| Yes | 183 (29.3%) | 143 (29.7%) | 24 (24.2%) | 15 (7.6%) |
| Positive family historya | ||||
| No | 1165 (95.8%) | 848 (95.2%) | 239 (98.4%) | 311 (94.8%) |
| Yes | 51 (4.2%) | 43 (4.8%) | 4 (1.7%) | 17 (5.2%) |
a
Positive family history defined as cases with two first- or second-degree relatives also affected with PTC.
PTC, papillary thyroid carcinoma; cPTC, classic PTC; fvPTC, follicular variant PTC; microPTC, microcarcinomas.