Table 2.
The Association Results for the GWAS Variants with PTC
| Frequency | |||||
|---|---|---|---|---|---|
| SNP | Locus | Cases(n = 1216) | Controls(n = 1416) | OR [CI] | p-Value |
| rs965513[A] | 9q22.33 | 0.47 | 0.33 | 1.81 | 8.20 × 10–24 |
| [1.62–2.04] | |||||
| rs944289[T] | 14q13.3 | 0.62 | 0.57 | 1.23 | 0.000489 |
| [1.09–1.38] | |||||
| rs116909374[T] | 14q13.3 | 0.06 | 0.03 | 1.90 | 0.00000754 |
| [1.44–2.53] | |||||
| rs2439302[G] | 8p12 | 0.52 | 0.45 | 1.30 | 0.00000511 |
| [1.16–1.45] | |||||
| rs966423[C] | 2q35 | 0.48 | 0.42 | 1.27 | 0.0000218 |
| [1.14–1.42] | |||||
GWAS, genome-wide association studies; OR, odds ratio; CI, confidence interval.