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. 2016 Sep 21;11:4819–4834. doi: 10.2147/IJN.S108847

Figure 10.

Figure 10

The surface functionalization of TNTs with BMP2 for cell proliferation and differentiation.

Notes: (A) Schematic illustration of the conjugation of BMP2 onto TNTs. Fluorescence images of MSCs adhered to (B) Ti, (C) BMP2-PDOP-Ti, (D) 30 nm TNTs, (E) BMP2-PDOP-30 nm TNTs. Cells were stained with actin filaments (red), cell nuclei (blue), and vinculin (green) in this study. Reprinted with permission from Lai M, Cai K, Zhao L, Chen X, Hou Y, Yang Z. Surface functionalization of TiO2 nanotubes with bone morphogenetic protein 2 and its synergistic effect on the differentiation of mesenchymal stem cells. Biomacromolecules. 2011;12:1097–1105.104 Copyright (2011) American Chemical Society.

Abbreviations: BMP2, bone morphogenetic protein 2; TNT, titania nanotube; MSCs, mesenchymal stem cells; PDOP, polydopamine.