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. 2016 Sep 22;10:3043–3051. doi: 10.2147/DDDT.S109545

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© 2016 Zhou et al. This work is published and licensed by Dove Medical Press Limited

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Proliferation effect of released TGF-beta 1 over bone mesenchymal stem cells.

Notes: The cells and RADA16 hydrogels contained TGF were co-cultured for 3 days (A), 7 days (B), and 14 days (C). CCK-8 assay for proliferated progeny (n=5). In the case of L-RADA16, a long-term effect of released TGF-beta 1 is evidenced by significantly higher total cell population. The TGF-beta 1 mitogenic activity can be appreciated till 2 weeks after being mixed with the self-assembling scaffolds. ^*P<0.05.

Abbreviations: TGF, transforming growth factor; OD, optical density.