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. 2016 Sep 20;11:4799–4818. doi: 10.2147/IJN.S111736

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© 2016 Freag et al. This work is published and licensed by Dove Medical Press Limited

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(A) DSC thermograms of (a) blank LCNPs, (b) AE-LCNPs (F6), (c) AE-PEGylated LCNPs (F13), and (d) free AE. (B) IR spectra of blank LCNPs, AE-LCNPs (F6), AE-PEGylated LCNPs (F13), and free AE. (C) XRD patterns of free AE (A), blank LCNPs (B), AE-LCNPs (C) (F6), and AE-PEGylated LCNPs (D) (F13). (D) In vitro release study of free AE, AE-LCNPs (F6), and AE-PEGylated LCNPs (F13) in phosphate buffer, pH 7.4; 1% Tween 80 at 75 rpm and 37°C using dialysis bag method.

Abbreviations: AE, aloe-emodin; DSC, differential scanning calorimetry; IR, infrared; LCNPs, liquid crystalline nanoparticles; PEG, polyethylene glycol; XRD, X-ray powder diffraction.