FIG. 5.

Linear regression analysis of toxicant induced changes in sperm mRNA levels with changes in retained spermatid heads (RSH) in the seminiferous tubules. The left panels depict the analysis from HD exposure while the right panels are from CBZ exposure. The circles, squares and triangles represent the different doses of HD and CBZ; 0.14, 0.21, and 0.33% HD, and 30, 50, and 70 mg/kg/day CBZ, respectively. The shaded grey region is the 95% confidence interval of the regression line (solid). R² values are shown and provide a goodness-of-fit measure. Animals with severe germ cell depletion were excluded from this analysis.