Superimposed local structures around the three S···O interactions additionally found in sPLA2-DG. Pictures were drawn using the structural data of PDB (Table 2) with dS···O≤0.10 Å. The sulfur, oxygen, nitrogen, and carbon atoms are shown in yellow, red, blue, and black, respectively. The residue numbers of Russell’s viper (r. viper) PLA2 are indicated. For the other snake PLA2, the residue numbers may be different (see the footnotes of Table 2). (A) The S(C27)···O(R36) interaction. (B) The S(C44)···O(C105) interaction shown with the bifurcated S(C44)···O(A40) interaction. (C) The S(C50)···O(F46) interaction.