Table 3.
Correlation analyses of different subgroups based on quartile ranges of hs-CRP concentrations and the corresponding cardiovascular risk factors.
Item | Subgroups Based on Quartile Ranges of hs-CRP (mg/L) | Correlation Coefficient a | p-Value | |||
---|---|---|---|---|---|---|
0–0.40 (n = 2392) | 0.41–0.80 (n = 1874) | 0.80–1.80 (n = 2087) | >1.80 (n = 2036) | |||
Age, years | 47.56 (7.97) | 49.67 (7.99) | 50.03 (8.00) | 50.91 (7.85) | 0.151 | <0.001 |
SBP, mmHg | 123.84 (18.43) | 128.38 (20.52) | 130.85 (20.33) | 133.6 (21.67) | 0.178 | <0.001 |
DBP, mmHg | 79.64 (10.94) | 82.14 (11.45) | 83.49 (11.65) | 84.93 (11.92) | 0.171 | <0.001 |
Glucose, mmol/L | 5.43 (1.02) | 5.68 (1.37) | 5.77 (1.49) | 6.09 (1.95) | 0.158 | <0.001 |
BMI, kg/m2 | 22.77 (2.90) | 24.07 (3.14) | 25.17 (3.64) | 25.69 (3.98) | 0.314 | <0.001 |
LDL-C, mmol/L | 2.60 (0.70) | 2.77 (0.76) | 2.83 (0.80) | 2.84 (0.82) | 0.119 | <0.001 |
HDL-C, mmol/L | 1.48 (0.33) | 1.4 (0.30) | 1.34 (0.30) | 1.31 (0.29) | −0.214 | <0.001 |
TC, mmol/L | 4.61 (0.83) | 4.79 (0.90) | 4.92 (0.95) | 4.92 (1.00) | 0.132 | <0.001 |
Non-HDL-C, mmol/L | 3.12 (0.78) | 3.39 (0.91) | 3.57 (0.93) | 3.61 (1.02) | 0. 206 | <0.001 |
Triglycerides, mmol/L | 1.29 (0.77) | 1.52 (1.08) | 1.79 (1.23) | 1.83 (1.29) | 0.191 | <0.001 |
LDL-C/HDL-C ratio | 1.82 (0.58) | 2.04 (0.67) | 2.18 (0.72) | 2.25 (0.74) | 0.236 | <0.001 |
LDL-C/TC ratio | 0.56 (0.07) | 0.57 (0.08) | 0.57 (0.08) | 0.57 (0.08) | 0.065 | <0.001 |
HDL-C/TC ratio | 0.33 (0.07) | 0.3 (0.07) | 0.28 (0.07) | 0.27 (0.07) | −0.281 | <0.001 |
Smoking, n (%) | 710 (29.7) | 661 (35.3) | 750 (35.9) | 756 (37.1) | 0.053 | <0.001 |
Hypertension, n (%) | 648 (27.1) | 710 (37.9) | 898 (43.0) | 1016 (49.9) | 0.159 | <0.001 |
Diabetes, n (%) | 108 (4.5) | 151 (8.1) | 214 (10.3) | 308 (15.2) | 0.122 | <0.001 |
High cholesterol, n (%) | 86 (3.6) | 131 (7.0) | 197 (9.4) | 204 (10.0) | 0.088 | <0.001 |
Data are presented as mean (standard deviation) unless indicated otherwise; a Correlation coefficient was estimated for the correlation analysis between hs-CRP concentrations and cardiovascular risk factors. Kendall’s tau-b correlation coefficient was calculated for smoking, hypertension, diabetes, and high cholesterol. For the remaining risk factors, Pearson’s correlation coefficient was calculated; hs-CRP, high-sensitivity C-reactive protein; SBP, systolic blood pressure; DBP, diastolic blood pressure; BMI, body mass index; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; TC, total cholesterol.