Table 2. Number and percentage of major pathogenic organisms isolated from all CSF specimens tested, as recorded in the NHLS CDW, in Gauteng province, South Africa, by year 2009 through 2012 (n = 11,891).
| 2009 | 2010 | 2011 | 2012 | Total | |
|---|---|---|---|---|---|
| Organism | n (%) | n (%) | n (%) | n (%) | |
| Cryptococcus neoformans | 2010 (59.1) | 1961 (62.7) | 1776 (63.2) | 1659 (65.0) | 7406 (62.3) |
| Mycobacterium tuberculosis | 935 (27.5) | 718 (23.0) | 666 (23.7) | 609 (23.9) | 2928 (24.6) |
| Streptococcus pneumoniae | 344 (10.1) | 341 (10.9) | 294 (10.5) | 218 (8.5) | 1197 (10.1) |
| Neisseria meningitidis | 32 (0.9) | 35 (1.1) | 18 (0.6) | 8 (0.3) | 93 (0.8) |
| Escherichia coli | 18 (0.5) | 23 (0.7) | 12 (0.4) | 19 (0.7) | 72 (0.6) |
| Haemophilus influenzae | 8 (0.2) | 4 (0.1) | 3 (0.1) | 5 (0.2) | 20 (0.2) |
| Listeria monocytogenes | 5 (0.2) | 4 (0.1) | 3 (0.1) | 4 (0.2) | 16 (0.1) |
| Salmonella non Typhi | 5 (0.2) | 6 (0.2) | 0 (0) | 4(0.2) | 15 (0.1) |
| Group: B Streptococcus | 6 (0.2) | 4 (0.1) | 5 (0.2) | 2 (0.1) | 17 (0.1) |
| Streptococcus pyogenes | 3 (0.1) | 3 (0.1) | 3 (0.1) | 0 (0) | 9 (0.1) |
| Other streptococci | 1 (0.03) | 1 (0.03) | 3 (0.1) | 1 (0.04) | 6 (0.1) |
| Mixed infections | 33 (1.0) | 29 (0.9) | 26 (0.9) | 24 (0.9) | 112 (0.9) |
| Total | 3400 | 3129 | 2809 | 2553 | 11891 |