Table 3. Treatment Related Toxicities.

This table demonstrates the numbers of events of major toxicities observed in patients treated with docetaxel and AT-101 for HNSCC

Grade 1–2
TOXICITY	Overall	Arm A (Docetaxel)	Arm B (Pulse Dose AT-101)	Arm C (Metronomic AT-101)
Anemia	39	17	14	8
Lymphopenia	33	9	15	9
Fatigue	15	7	5	3
Thrombocytopenia	7	4	1	2
Alopecia	4	2	1	1
Nausea	3	0	3	0
Neutropenia	2	2	0	0
Grade 3–4
TOXICITY	Overall	Arm A (Docetaxel)	Arm B (Pulse Dose AT-101)	Arm C (Metronomic AT-101)
Lymphopenia	11	4	4	3
Anemia	5	4	1	0
Nausea	2	1	1	0
Vomiting	1	0	1	0
Peripheral Edema	1	0	1	0
Hypoxia	1	0	0	1
Neutropenia	4	3	1	0