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. 2016 May 17;9(5):657–660. doi: 10.1093/ckj/sfw038

Table 1.

Summary of clinical presentations, anti-GBM antibodies, renal biopsy and treatment

Year Clinical presentation Anti-GBM antibodies Renal biopsy Treatment
2001 Gross hematuria; no pulmonary symptoms Undetectable Crescentic glomerulonephritis with 25% crescents on light microscopy; Linear deposition of IgG on immunofluorescence microscopy
  • Plasmapheresis 3 days/week × 7 occurrences

  • Prednisone 60 mg/day × 6 months

  • Cyclophosphamide 2 mg/kg/day × 6 months

2006 Dyspnea, hemoptysis, gross hematuria; Diffuse alveolar hemorrhage on chest plain film and CT 112 AU/mL Not obtained
  • Plasmapheresis daily × 7 days

  • Methylprednisone 1 mg IV × 3 days followed by prednisone 40 mg × 2 months

  • Cyclophosphamide 2 mg/kg/day × 32 months

2014 Epistaxis, hemoptysis; diffuse alveolar hemorrhage on chest plain film and microhematuria on urine analysis Undetectable Not obtained
  • Plasmapheresis daily × 7 days

  • Methylprednisone 1 mg IV × 3 days followed by prednisone 60 mg × 2 months

  • Cyclophosphamide 2 mg/kg/day × 3 months