Figure 2.

Correlation of education and cortical thickness. The figure illustrates the association of the years of education and cortical thickness across medial temporal subregions (legend see Figure 1). Patients homozygous for the APOE4 allele or APOE4 carriers with a first-degree family history of Alzheimer’s disease showed a positive correlation of education and thickness in all regions except CA1. Patients with an intermediate risk profile (APOE4 heterozygosis or family history risk) showed this correlation only in PHC with trends for other regions, such as the ERC. Patients in the low risk group (no APOE4 allele and no family history) did not show an association between education and thickness.