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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: J Neurochem. 2016 Aug 15;139(1):134–148. doi: 10.1111/jnc.13734

Figure 6.

Figure 6

L-DOPA (5 mg/kg) induced rotational behavior is significantly attenuated in P2X4R KO mice. IVM (5 mg/kg) significantly potentiated L-DOPA's effect on the number of contralateral turns in WT and P2X4R KO mice (A). IVM' ability to enhance L-DOPA induced motor behavior was significantly altered in P2X4R KO mice (B). Values on the y-axis represent the mean of number of contralateral turns per 10 minute interval ± SEM from 14 WT, 8 P2X4R KO. *P<0.05, *** P <0.001 versus L-DOPA treated WT mice, ## P<0.01 versus L-DOPA treated P2X4R KO mice for (A), *P<0.05 versus WT mice for (B), Bonferroni post hoc test.