Table 2.

Number of days on which enteral intake was >50% breast milk and estimated brain volumes at term equivalent age

	Model 0 n=147		Model 1 n=133		Model 2 n=132		Model 3 n=131
	β indicates cc increment in estimated brain volume per 1 additional day on which breast milk was >50% of enteral intake during the first 28 days of life
	β	95% CI	β	95% CI	β	95% CI	β	95% CI
Intracranial volume	−0.05	−2.05, 1.05	−0.22	−1.93, 1.50	−0.42	−1.84, 0.99	−0.30	−1.57, 0.97
Total brain size	−0.07	−1.36, 1.22	0.18	−1.25, 1.61	0.00	−1.21, 1.21	0.06	−1.06, 1.17
Total gray matter	−0.29	−1.12, 0.55	−0.20	−1.12, 0.73	−0.32	−1.17, 0.53	−0.29	−1.11, 0.52
Total white matter	0.10	−0.58, 0.77	0.20	−0.54, 0.94	0.17	−0.48, 0.82	0.19	−0.42, 0.81
Myelinated white matter	−0.01	−0.10, 0.09	−0.03	−0.12, 0.07	−0.03	−0.12, 0.07	−0.02	−0.12, 0.07
Unmyelinated white matter	0.10	−0.56, 0.76	0.21	−0.52, 0.94	0.17	−0.46, 0.81	0.19	−0.41, 0.79
Deep nuclear gray matter	0.11	0.02, 0.20	0.14	0.05, 0.23	0.15	0.05, 0.25	0.15	0.05, 0.25
Cerebellum	0.03	−0.07, 0.12	0.04	−0.06, 0.15	0.03	−0.07, 0.12	0.03	−0.06, 0.11
Hippocampus	0.003	−0.004, 0.01	0.003	−0.01, 0.01	0.001	−0.01, 0.01	0.002	−0.01, 0.01

CI is confidence interval.

Model 0 is adjusted for exact age at assessment, gender, gestational age at birth

Model 1 = Model 0 + social risk score

Model 2 = Model 1 + multiple gestation, Clinical Risk Index for Babies score, antenatal or postnatal corticosteroids, neonatal illness (supplemental oxygen dependency at 36 weeks, sepsis or necrotizing enterocolitis)

Model 3 = Model 2 + birth-to-term weight z-score change