Table 3.
Characteristics of infants who received a single course (two doses) of betamethasone: comparison of those who delivered less than 10 days after the first betamethasone dose with those who delivered greater than or equal to 10 days after the first betamethasone dose
| Characteristic | Time to delivery after 1st dose of betamethasone | P value | |
|---|---|---|---|
|
| |||
| <10 days (N = 312) |
≥10 days (N = 80) |
||
|
| |||
| Birth year epoch (%) | 0.012 | ||
| 1998 – 2003 | 39 | 21 | |
| 2004 – 2009 | 33 | 43 | |
| 2010 – 2015 | 28 | 36 | |
|
| |||
| Preeclampsia (%) | 26 | 13 | 0.013 |
|
| |||
| Gestational Diabetes (%) | 6 | 14 | 0.030 |
|
| |||
| Clinical Chorioamnionitis (%) | 25 | 29 | 0.494 |
|
| |||
| Cesarean Delivery (%) | 69 | 71 | 0.726 |
|
| |||
| Presentation at delivery (%) | 0.483 | ||
| Vertex | 60 | 66 | |
| Breech | 34 | 28 | |
| Transverse | 6 | 6 | |
|
| |||
| Multiple Gestation (%) | 29 | 48 | 0.001 |
|
| |||
| Caucasian (%) | 46 | 55 | 0.158 |
|
| |||
| Outborn (%) | 10 | 10 | 0.917 |
|
| |||
| Gestational age <26 weeks (%) | 48 | 11 | <0.0001 |
|
| |||
| Gestational age (mean ± SD) | 25.8 ± 1.1 | 26.7 ± 0.7 | <0.0001 |
|
| |||
| Small for gestational age (%) | 26 | 5 | <0.0001 |
|
| |||
| Birth weight-gm (mean ± SD) | 766 ±193 | 919 ± 183 | <0.0001 |
|
| |||
| Male (%) | 50 | 43 | 0.231 |
|
| |||
| 5 minute Apgar score ≥6 (%) | 69 | 73 | 0.561 |
|
| |||
| Prophylactic indomethacin (%) | 69 | 71 | 0.726 |
|
| |||
| Early Onset Sepsis (%) | 4 | 8 | 0.216 |
|
| |||
| Time to delivery *- days (mean ± SD) | 3.9 ± 2.1 | 14.9 ± 4.0 | <0.0001 |
*
Time to delivery after 1st dose of betamethasone; all infants delivered at least 24 hours after the 1st dose of betamethasone